Methamphetamine bio chemical
All drugs that have an addictive quality have two things in common. They produce an initial pleasurable effect on the user, followed by a rebound unpleasant effect. An amphetamine, like crystal meth, through its stimulant effects, produces a positive feeling. Nonetheless, when the effect wears off, it leaves the individual with the opposite feelings. This is due to the suppression of the normal production of adrenaline by the drug. Now, a chemical imbalance has occurred and the result is irritability that physically requires more of the drug to go back to feeling normal and good again. This pleasure/tension vicious cycle leads to loss of control over amphetamines or any other addictive drug.
The brain’s reward system consists of different drives and needs of the body; sex, hunger, thirst and friendship. When these urges are satisfied, or when pain is relieved, a signal is sent to certain brain cells which produces a chemical substance that signals reward. When these monitor cells have been stimulated, a signal is sent to the tip where a minor quantity of this reward chemical is released. The chemical or neurotransmitter then reaches and stimulates the reward center, creating a feeling of well-being.
Crystal meth is able to manufacture these artificial feelings of pleasure. The majority of addictive drugs are able to manufacture pleasurable effects by chemically copying some normal brain messenger chemicals which produce positive feelings in response to signals from the brain. A wonderful instance of this is the narcotic drug morphine which copies endorphin (nature's natural pain reliever). When the drug comes in, it stimulates the reward center. This short circuits the survival mechanism, due to the fact that the reward center cell can't tell the difference between the drug and the natural chemical messenger. Frequently, the result is addiction and dependence to the instantaneous, fast, and predictable drug which caused the effect. While this is happening, the user’s brain short circuits in a way leaving their brain less able to make life’s usual rewards work for them. When the amphetamine molecule goes through the blood stream, it bypasses the natural nerve cells and causes the artificial release of normal, chemical messengers for positive feelings. What occurs as a result of this is a sensation of satisfaction, well-being and relief. Then, instantaneously, the system sends a signal of positive rewards back to the memory of this activity. The first of several pleasure hooks has been implanted into the memory. The amphetamine drug lies to both the reward center and to the monitor cell. The cell then adapts to the excess stimulating effect of amphetamine by shutting down manufacture of the natural stimulatory chemistry, attempting to keep a balance.
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